The purpose of this module is to develop the skills needed to align pairs of sequences with Geneious Prime. Pairwise sequence alignment allows you to match regions in sequences to identify probable structural and functional similarities.
In this module, we will look at aligning nucleotide (DNA) and polypeptide (protein) sequences using both global (Needleman and Wunsch) and local (Smith and Waterman) alignment methods.
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Introduction: Alignment algorithms
Exercise 1: Using dotplots to explore relationships
Exercise 2: Aligning DNA sequences
Exercise 3: Aligning protein sequences